FDA-approved and NCCN-guideline-included ‌China-originated EGFR-targeted drug Shuwotinib

On July 10, 2025, NCCN released the latest (Version 7.2025) of its ‌Non-Small Cell Lung Cancer (NSCLC) Clinical Practice Guidelines‌, incorporating ‌Sunvozertinib as a ‌post-line therapy option‌ f‌advanced metastatic NSCLC patients with EGFR exon20ion mutations (EGFR Exon20ins)‌. This recommendation applies to patients who have progressed after first-line treatment.

HLA Neoantigens

HLA (human leucocyte antigen, human white blood cell antigen) is a group of highly polymorphic genes.

The silent majority is also the overlooked majority.

‌"Diseases of affluence,"‌ also known as ‌"modern civilization diseases,"‌ refer to non-communicable epidemics that arise as people enter modern affluent societies. With improved dietary conditions but reduced physical activity, these conditions include:

Long-term inflammation turns cancerous? Ignoringonic GI inflammation may trigger cancer development

I once heard an incredible report about an auntie Liu from Zhejiang. Twenty years ago, her right foot was crushed by a car, leaving a wound that never fully healed. The injury remained inflamed, but Auntie Liu, being carefree, simply kept changing the dressings never paid much attention to it.

Can't Understthe Variants in the Report? After Reading This Article, You'll Be Clear

When you receive an NGS (Next-Generation Sequencing) report, are you confused by the various letters, numbers, symbols used to describe gene variants? After bioinformatics analysis, sequencing data is annotated according to HGVS (Human Genome Variation Society) guidelines. Once you grasp the notation rules explained in this article, the report will become crystal clear.