Beyond surgery, chemoradiotherapy, targeted therapy, and immunotherapy, what other "new weapons" are available for cancer treatment?

Based on their mechanisms of action, this review categorizes over ten emerging tumtherapy modalities into three majclasses: targeted payload delivery, immune cell-mediated cytotoxicity, disruption of intrinsic signaling pathways. Due to space constraints, each class of drugs therapeutic approaches is briefly introduced, with concise coverage.

【Case sharing】Dynamic monitoring of colorectal cancer ctDNA to guide anti-HER2 "re-challenge", with multiple benefits for two patients with metastatic colorectal cancer

This article shares two cases of patients who repeatedly used plasma NGS HER2 results as a reference in the entire treatment line, continuously adjusted the treatment plan, showed certain clinical benefits.

Antipyretic, antidiabetic, weight loss, male gynecology: four old drugs are being targeted by scientists to fight cancer

Drug development often takes ten years costs billions of dollars, so scientists turned their attention to another path - "old drugs fnew uses": to use drugs that have been on the market fmany years have clear safety to fight new battles. In the field of oncology, several unexpected "players" were listed, coming from the fever-reducing drug counter, diabetes prescription, weight loss injection, urology pharmacy.

【Case Selection】What should I do if I have a rare EGFR mutation in lung cancer? Osimertinib achieves complete PET-CT remission in stage IVA lung adenocarcinoma

The case shared in this article is that of a patient with non-small cell lung cancer in the IVA stage with a relatively rare G719A + L861Q compound mutation. After 3 months of treatment with osimertinib, PET-CT showed that all FDG high-uptake target lesions had completely resolved, achieving complete remission.

New product launch - 26-gene RNA detection for solid tumors, improved fusion gene detection, more targeted benefits

In the era of precision oncology, genetic testing has become the core means of guiding targeted therapy. However, many patients face a dilemma: the DNA level test does not find a drug target, but there is still hope ftreatment - the problem may be that the "fusion gene" is missed. Inder to meet the clinical needs, our company has launched a 26-gene detection package at the RNA level, which has greatly improved the detection rate accuracy of gene fusion, provided more possibilities ftargeted drug use ftumpatients.

In a medical examination report that can span dozens of pages, which items are closely related to tumors?

Many people are accustomed to flipping directly to the 'Summary' section at the beginning of their medical report. Upon seeing 'No significant abnormalities detected,' they let out a sigh of relief file the report away in a drawer. But did you know? Some 'clues' related to tumors are not explicitly stated in the summary—they are hidden within the details of various examination items.

FDA-approved and NCCN-guideline-included ‌China-originated EGFR-targeted drug Shuwotinib

On July 10, 2025, NCCN released the latest (Version 7.2025) of its ‌Non-Small Cell Lung Cancer (NSCLC) Clinical Practice Guidelines‌, incorporating ‌Sunvozertinib as a ‌post-line therapy option‌ f‌advanced metastatic NSCLC patients with EGFR exon20ion mutations (EGFR Exon20ins)‌. This recommendation applies to patients who have progressed after first-line treatment.

HLA Neoantigens

HLA (human leucocyte antigen, human white blood cell antigen) is a group of highly polymorphic genes.

The silent majority is also the overlooked majority.

‌"Diseases of affluence,"‌ also known as ‌"modern civilization diseases,"‌ refer to non-communicable epidemics that arise as people enter modern affluent societies. With improved dietary conditions but reduced physical activity, these conditions include:

Long-term inflammation turns cancerous? Ignoringonic GI inflammation may trigger cancer development

I once heard an incredible report about an auntie Liu from Zhejiang. Twenty years ago, her right foot was crushed by a car, leaving a wound that never fully healed. The injury remained inflamed, but Auntie Liu, being carefree, simply kept changing the dressings never paid much attention to it.

Can't Understthe Variants in the Report? After Reading This Article, You'll Be Clear

When you receive an NGS (Next-Generation Sequencing) report, are you confused by the various letters, numbers, symbols used to describe gene variants? After bioinformatics analysis, sequencing data is annotated according to HGVS (Human Genome Variation Society) guidelines. Once you grasp the notation rules explained in this article, the report will become crystal clear.